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Abstract: Administration of ACTH stimulates adrenal secretion of progesterone as well as corticosterone (Resko, 19691; Feder et al., 1969; Feder et al., 1971; Piva et al., 1973). Progesterone is both an obligatory intra-adrenal substrate for corticosterone production and a steroid essential for maintenance of pregnancy. Thus, the regulation of adrenal steroidogenesis during pregnancy has two potentially important aspects: i.) Maintenance of optimal blood levels of corticosterone and ii.)Contributing significant amounts of progesterone to the total maternal pool. Since the extended luteotrophic function of ovary in rat & mice during pregnancy is related to the Peroxidase-Ascorbate system (Agrawal, P. & Laloraya, M.M. 1979). It appears likely that synthesis of progesterone under the action of ACTH during pregnancy may be controlled by a similar mechanism as reported for LH in the ovary, thus causing increased synthesis and secretion of the Progesterone and corticosteroids from the adrenal gland.

Title: Histochemical Studies of Enzymes in the Adrenal Gland of Rat & Rabbit during Pregnancy
Author: Dr.Shobha Chaturvedi, Dr. Vibha Dave
International Journal of Recent Research in Life Sciences (IJRRLS)
Paper Publications

Abstract: Rubella, though a mild skin infection but show disastrous effects during pregnancy and causes damage to fetus. The disease is vaccine- preventable diseases can manifest with severe teratogenic effects in fetus known as congenital rubella syndrome (CRS) due to primary maternal infection such as heart disorders, blindness, deafness or other    life threatening organ disorders. During pregnancy, explore to disease can lead to disastrous results such as bad obstetric history (BOH), repeated pregnancy loss (RPL) or may cause deformities in fetuses whereas it also responsible for infertility and maternal mortality. In the study162 women of different background were selected, out of them 27.16 % of them were found seronegative and were at risk to have Rubella infection. In the study, the pregnant women show variation in immunity for Rubella according to age. The highest number of susceptible women was found in age group 21-25 year which is crucial age of conceiving.

Keywords: Teratogenic, deformities, seronegative, immunity, susceptible.
Title: Impact of Rubella on Pregnancy With Respect To Igm Immunolobulin
Author: CHETNA SAVITA, Dr. HEMLATA JHARBADE,Dr. G.D SHARMA
International Journal of Recent Research in Life Sciences (IJRRLS)
ISSN 2349-7823
Paper Publications

Abstract: In vitro mutation induction by using gamma ray at 20, 30, 40 and 60Gy was used to generate variability in triploid banana "Berangan cv. Intan (AAA), so as to provide the opportunity to select plants with desirable characters such as early fruiting and short stature. Mutation frequency increased with increased dosage whereas, survival and capacity to regenerate decreased with increased doses. Time to initiation varied from 4-8 weeks for gamma-irradiated materials compared to 2-3 weeks in the control. It appeared that the higher the dose, the longer it took for shoot initiation. The exposure of shoot-tip meristem pieces to radiation doses produced wide variation in growth and morphogenetic performance. Mutagenic treatments induced 2 to 3- fold increases in variability in both quantitative and qualitative traits at different stages, in vitro; at nursery and field. For the field-grown plants; the proportion varied from 2.9% for the control plants to 16.8% for 60 Gy and 20.1% for 40 Gy-treatments, while for treatments at 20 and 30 Gy variations was at 18% and 19.2%, respectively. The frequency of variants was highest in 40 Gy followed by 30 Gy and 20 Gy, while it was very low in 60 Gy except for plant stature (dwarfism or stunted growth). Earliness to flowering variants were recorded at 20, 30 and 40 Gy at low frequencies (0.6%, 0.7% and 1.7%) respectively, while none was observed for 60 Gy treatments. As in vitro mutation induction could create genetic variability as well as many undesirable variants, it is highly desirable to integrate in vitro mutation with a selection system that can screen for large mutagen treated population. The useful variants recorded for earliness to flowering were selected for 30 and 40 Gy treatments. 40 Gy showed high frequency in earliness as compared with 20 and 30 Gy., which came to flowering as early as 6 – 6.5 months compared to 7-8 months for control. The useful dwarf, which considered as desirable traits, showed a balance of height and girth.

Keywords: Musa spp.- mutation breeding- gamma irradiation (Gy)
Title: Mutation Induction for Improvement of Banana (Musa Spp). "Berangan Cv. Intan-AAA"
Author: Shadia Abdelgadir Rayis, Abubaker A.Abdallah
International Journal of Recent Research in Life Sciences (IJRRLS)
ISSN  2349-7823
Paper Publications

Abstract: In situ changes in the enzymes i.e.∆5 3β- Hydroxysteroid dehydrogenase, Peroxidase,Cytochrome oxidase, Acid and Alkaline phosphatases and lipids in the Interrenal Gland and Ovary at different stages of reproductive cycle in fish, Cyprinus carpio had been studied.Peroxidase appears to be involved in the biosynthetic machinery controlling corticosteroidogenesis. Peroxidase and Cytochrome oxidase would also seem to transform adrenocortical cells and hypertrophied theca interna into highly oxidative compartments of the adrenal and ovary which attributes to the oxidation of pregnenolone to progesterone and corticosteroids towards maturation and ovulation of the oocyte from the ovary.

Keywords: Biosynthetic machinery, Enzymes studies, Adrenal-Ovary Interrelation, Pregnenolone to progesterone, Corticosteroids.
Title: HISTOCHEMICAL STUDIES OF ENZYMES INVOVED IN HORMONAL REGULATION IN FISH (Cyprinus carpio)
Author: Dr. Shobha Chaturvedi, Dr. Vibha Dave, Prof. Raksha Modi
International Journal of Recent Research in Life Sciences (IJRRLS)
ISSN 2349-7823
Paper Publications

Abstract: Ebola virus disease (EVD) formerly known as, Ebola haemorrhagic fever (EHF) is one of the most severe viral HFs often characterized by the sudden onset of fever, intense weakness, muscle pain, headache, sore throat, vomiting, diarrhoea, rash, impaired kidney and liver function, and in some cases, both internal and external bleeding. The 2014 Ebola outbreak is the largest Ebola outbreak in history and the first Ebola outbreak in West Africa affecting multiple countries in West Africa e.g. Guinea, Liberia, and Sierra Leone. The current outbreak threatens to spread more and cross the boundaries of West Africa to establish itself in realms of different continents. India is also vulnerable due to its susceptible ecosystem and unprepared health system. Our healthcare systems as well as communities are clearly not sensitised to the extent of the danger this possess, it’s time to take action before it is far too late.

Keyword: Ebola Virus Disease, Outbreak, West Africa, Laboratory Diagnosis, Vaccine, Prevention.
Title: Ebola Virus Disease: An Emerging Global Public Health Concern
Author: Dr. Monalisha Sahu, Dr. Deepak Dhamnetiya
International Journal of Recent Research in Life Sciences (IJRRLS)
ISSN: 2349-7823
Paper Publications